Transgender man medical care
I recently attended a medical conference and listened to a fabulous transgender care lecture. Here are the pearls that I learned…
Masculinizing medications:
Only testosterone.
- Goal of testosterone is 300 – 1000. There is large range for testosterone. Testosterone level over 1000 causes problem with increased red blood cell mass.
- The masculinizing change takes upwards of 3-5 years for masculinization to take effect. Usually within 6 months, the voice has completely changed and this is an irreversible effect of testosterone.
- Testosterone cypionate is usually given under the skin (and does not need to be injected into the muscle). Gel is a popular option, but these are expensive and often not covered by insurance. Testosterone pellets (Testepell) is used as a subdermal implant that is inserted every 3 months.
- Labs: testosterone level.
- Estradiol level does not matter much.
- Goal for testosterone is within the male-range. Monitor red blood cell mass. Hematocrit less than 55 is the goal. Be sure to hydrate with water with blood work drawn.
Masculinization surgery:
- Removal of uterus and ovaries. Ob/gyn perform this surgery.
- After 2 years of testosterone the clitoris can be formed into a phallus. Metoidioplasty (done at many sites) and phalloplasty (staged surgeries over a year or two. Complicated. Only done at a few centers around the country) may be considered.
Patients still need primary care!
Physician should take organ-inventory to make sure that all organs are screened for.
- For example, transgender men who have a cervix need pap smears to screen for cervical cancer).
- If transmen miss a testosterone dose (and have vaginal intercourse with men) they can get pregnant. What is the contraception method?
- Mammogram. If breasts were mostly removed and chest contouring was performed, there is still some breast tissue present. Consider breast u/s or MRI may be needed (there may not be enough breast tissue to squeeze in a mammogram machine).
I hope this helps…

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