We have begun using progetogens to reduce the risk of miscarriage. This significantly decreases the rate of miscarriage compared to placebo.

How common are miscarriages? Miscarriages occur in 15 to 20% of pregnancies. A “threatened” miscarriage is defined as any vaginal bleeding (with or without pain) in a pregnant woman with a closed cervix and an otherwise viable fetus inside the uterus.

What is NOT found to help? Bed rest, pelvic rest (nothing in the vagina meaning no sex, douching or tampons), vitamins, uterine relaxants, and administration of beta HCG. Progestogens (medications that mimic progesterones) may help. A meta-analysis of 7 research studies with nearly 700 women showedthat oral administration of progestogens had a lower risk of miscarriage compared to those receiving placebo.

The National Institute for Health and Care Excellence is currently developing a guideline with regard to progestogens and miscarriage. More research is definitely needed.

For more information: http://www.cochrane.org/CD005943