The prevalence of oral human papillomavirus is nearly three times higher in men than in women. You may ask “Why does this matter?”… oral HPV infection causes a subset or oropharyngeal squamous cell carcinoma (OSCC).
- HPV type 16 is the subtype of HPV associated with OSCC.
- The peak prevalence of oral HPV occurred in people aged 30-34 (7.3%) and 60-64 years (11.4).
- The risk increased significantly as the number of sex partners for any type of sex increased.
- Cigarette smoking increases risk of oral HPV infection.
- The incidence of HPV-positive oropharyngeal cancers increases 225% between 1988 and 2004.
Studies are needed to test HPV vaccines against oral HPV infections.
Source: JAMA 2012; 307