Cancer screening key issues. Why, who, which test do we use?

flickr.com/photos/ saturnino/ 1813270775

flickr.com/photos/ saturnino/ 1813270775

I recently read a great article demonstrating biases in the evaluation of screening tests. This is timely as last week I had a 75 year old female visibly upset that she no longer needed regular pap smears. She sighed and said “I guess no one cares if I die of cervical cancer.”

Cancers have different growth rates—which determines their potential to be detected by screening.   Also there are different characteristics of the disease. How fast does the cancer grow? Might the early-stage abnormalities regress on its own (without treatment)? Is there effective and acceptable treatment available? Are patients asymptomatic for a time during which detection and treatment will significantly reduce morbidity and mortality?  Do we have an effective screening test during the time that we could “catch” the problem in time to save their life?

What are the characteristics of the screening test?  Is the test sensitive enough to detect the disease during the asymptomatic period? Is the test specific enough to minimize false positives (a false positive test shows you have the disease, but indeed, you do not)?

What are the characteristics of the screened population? At what age is which screening test appropriate? (Should we test 10 year-olds for colon cancer?) Are patients willing to comply with subsequent tests and therapy if needed?

 

What does all this mean? Researchers are pooling studies to give us more insight into which tests should be performed in which patients. This is so that there is less chance of false positives (which leads to patient worry and further work ups) and more chance to find those most at risk. I think medical school ingrained in me a perpetual weighing of risks and benefits.

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Mindless weight loss

flickr.com/ photos/ reallyboring/ 2860775800

flickr.com/ photos/ reallyboring/ 2860775800

This would be great, right?  Well, if you use the following rules, then you will mindlessly eat less and may lose weight.

keep kitchen counters clear.  The only exception is you can keep a bowl of fruit in sight.  There should be no visible snack food, no nuts, no bread, not even breakfast cereal in sight.  When there is food in sight, we tend to nibble.  And, the nibbling adds up.

To trick yourself into drinking less wine, use taller white wineglasses.  The shape of the glass and the red-color of red wine help us drink less.  If it is easier to see we pour “9 percent less red wine.”

Sit in well-lit areas of restaurants (near windows or doors) as we tend to eat less when we can see our food better.  Also, ask for a doggie bag and take 1/2 your meal to go.  It’s best to ask for this before you are even served.

Keep fruit on the top shelf of the refrigerator.  When good-for-us food is at eye-level we are more likely to  opt for this instead of more caloric options.

Make environmental changes so that you are not tempted.  You’ll just eat less.

Brian Wansink Ph.D. has penned a new book “Slim by Design: Mindless Eating Solutions for Everyday Life.” He is an entertaining writer and impeccable researcher.  Enjoy!

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Recognizing and treating teen depression

.flickr.com/photos / blushingmulberry/ 4001277317/

.flickr.com/photos / blushingmulberry/ 4001277317/

October is national Mental Health Awareness month.    No one is immune from mental illness.  Adolescents are especially vulnerable to mental illness and are a major at-risk population for developing severe depression.  The Centers for Disease Control and Prevention show that nearly one in six high school students have considered suicide and one in 12 have attempted suicide

The National Institutes of Mental Health note that suicide is the third leading cause of death among adolescents.

Teenage depression can be scary for parents who may observe changes in their child.  Behaviors to watch for are

  • irritability,
  • loss of interest in activities,
  • personality change,
  • sadness or hopelessness,
  • changes in sleeping and eating habits,
  • thoughts of suicide,
  • difficulty concentrating or focusing.

If teenager is suicidal or in immediate danger, the teen should be brought to the emergency room or crisis center.  Call 911, if needed. 

Treatment for adolescent depression can involve antidepressant medication, psychotherapy or a combination of both medicine and counseling. 

If you see a change in your teen, talk to them about depression.  It is a difficult topic to approach, but it can be life saving.

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Which complementary medicine modalities are worth doing?

flickr.com /photos/tingy /484468

flickr.com /photos/tingy /484468

Consider taking fish oil to decrease high triglycerides.   The American Heart Association recommends 2 to 4 grams per day of fish oil with DHA to help decrease triglycerides.   The most common side effects of fish oil is bloating and belching and should not be given after an acute bleeding event.

 

Oral glucosamine sulfate may reduce osteoarthritis pain and improve joint function. Glucosamine is an amino sugar that is considered a building block of cartilage proteoglycans. It occurs naturally in the body, but the glucosamine in supplements is from seashells. Glucosamine stimulates components of the knee to help delay joint degeneration. Glucosamine 500 mg three times a day was found to be significantly helpful in studies.

 

Antibiotic-associated diarrhea is a common problem. Probiotics can prevent antibiotic-associated diarrhea. The studies showing this benefit gave between 5 billion to 40 billion colony forming units per day. The most commonly used probiotics are from Lactobacillus and Saccharomyces genera. These are considered relatively safe, but are not recommended for immunocompromised people or those with an indwelling medical device.

 

Acupuncture should be considered as an additional modality to help patients with chronic low back pain. Also, yoga has helped with both short-term and long-term decrease in back pain.   For more information see http://bit.ly/yoga-as-therapy

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Warts. Do I need to treat them?

No. 

There was a study of 1100 children. 1 of 3 of them had at least one wart.  One year later (without any treatment) 1/2 of all the warts were gone.  This was especially true in younger and nonwhite children.

So, if you can wait it out… all your children’s warts may resolve spontaneously and without treatment. 

flickr.com /photos/ sea-turtle/6061032366

flickr.com /photos/ sea-turtle/6061032366

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Do you need to fast before cholesterol lab?

No…  but, occasionally yes. 

A study of over 209,000 cholesterol labs found that if we are only looking at total cholesterol and LDL (bad) cholesterol, that patients do NOT need to fast. 

The triglycerides (another part of the cholesterol/lipid panel) will be elevated by less than 20% if taken nonfasting compared to fasting.

So, this means, that unless I am concerned about high triglycerides, the patient can have lab drawn conveniently during an office appointment regardless of timing of last meal.

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Notice: hydrocodone will be more difficult to refill!

You may not take the popular pain medicine hydrocodone (also known as Vicodin, Lortab, and Norco).   But, if you do… refills are going to be more difficult starting today.  The Drug Enforcement Administration is changing hydrocodone to a stricter drug class. 

Why?  The DEA cites 7 million Americans who abuse prescription drugs and 100,000 deaths from overdoses in the past 10 years. 

What are the changes?  Hydrocodone pain medicine will only be given by pharmacies in 30-day supplies.  No refills will be allowed on a prescription.  Each prescription must be handwritten by a doctor (no faxing or phoning in a prescription).  Only physicians can write for hydrocodone (no midlevel providers like physician assistants or nurse practitioners).

The intent of this new rule is for the physician to make a conscious review of the case monthly and consider if this medication should be refilled.  I think this is a good rule.  Let’s see how it plays out…

Posted in General Medicine- Adults, medication issues | Comments Off on Notice: hydrocodone will be more difficult to refill!

Gallstones

flickr.com /photos/tingy /484468

flickr.com /photos/tingy /484468

What should you do if you have gallstones?  Gallstones are just that… stones that form in the gallbladder.  The gallbladder resides in the upper right side of our abdomen.   Did you know that 50-70% of patients with gallstones have NO symptoms.

A recent study followed gallstone patients for 25 years.  Patients developed symptoms from those gallstones at a rate of 1-2% per year. For this reason, it is reasonable to follow patients along (do not do surgery–but instead watch for gallbladder colic symptoms).  It is recommended that patients who are at high risk of biliary cancer and other operative or disease-related complications can be offered a prophylactic cholecystectomy (having the gallbladder removed without current pain) if the benefits of surgery outweigh the risks of observation.

Indications for consider of prophylactic cholecystectomy are those at risk of carcinoma (those with an ultrasound showing “porcelain” gallbladder, those of Native North or Southern American background, when cysts are also in the bile ducts, or a polyp in the gallbladder bigger than 1 cm).  Otherwise, patients may consider removing the gallbladder if there are gallstones larger than 3 cm, if the patient lives far away from a healthcare facility, those with sickle cells disease or those who have had an organ transplant or are immunosuppressive therapy.

Hope this helps.

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Head lice

flickr.com/ photos/47361363 @N00/4829032462

flickr.com/ photos/47361363 @N00/4829032462

I know…it’s hard to NOT be disgusted if you  or your child gets head lice.  But, don’t overreact.  It’s benign.  It’s treatable. And, it’s nothing to feel dirty about.

The head louse (the plural of louse is lice) is a parasitic insect that can be found on the eyebrows, eyelashes and scalp.  The lice live close to the scalp and feed on human blood several times a day.   In the United States, head lice are most common among daycare-attending preschool children, elementary school children,k and household members of infested children.

If you get head lice it does not mean you are unclean.  Personal hygiene or cleanliness in the home/school have little to do with contracting lice.  Lice crawl (they cannot fly or hop).

The method of spreading lice can be

  • Direct head-to-head contact with the hair of an infected person is one method of spread,
  • sharing clothing or combs, brushes or towels,
  • lying on a couch, pillow or bed after an infested person has.  (If lice fall off the scalp they die within one to two days and lice eggs die within a week.)

Pets do not spread head lice.

Symptoms of head lice are ticking feeling on the scalp, itching caused by an allergic reaction to the bite, emotional irritability, difficulty sleeping, sores on the head after bouts of scratching.

What should you do if you suspect head lice?

  1. Inspect the head for eggs (also called nits that look like white/yellow/ brown knots on the hair), nymphs (young lice) and adults (6-legged beige or gray insect the size of a sesame seed).
  2.  If one member of the family has lice, check everyone else’s scalp.
  3. Treat anyone infected.

Here’s how to treat head lice.

  • Call your physician if child under age 3 for an appropriate medication.
  • If older than 3, over-the-counter medicines are usually sufficient.
  • Use fine-toothed comb to remove lice and eggs.
  • Follow package instructions.
  • Repeat treatment after 7 to 10 days to kill any eggs that have hatched after the first treatment.
  • Do not use hair conditioner before lice treatment.  The conditioner coats the hair and prevents the lice medicine from being effective.
  • Do not wash hair for two days after treatment.

What else needs to be done in the home?

  • Machine-wash and dry in hot air cycle any bedding, clothing, hats, scarves or towels used the 2 days before lice treatment.
  • For items that cannot be laundered may be dry-cleaned or sealed in a plastic bag for 2 weeks (as the lice will all die by then).
  • Soak combs and brushes in hot water (130 degrees Fahrenheit or more) for 10 minutes.
  • Vacuum furniture and flooring to remove any hairs that may have viable nits attached.
  • Exterminators are not necessary.
  • If after 8 to 12 hours after treatment, lice seem as active before on the scalp, the medication may not be working and the lice may be resistant to the medication you have tried.  If so, call your physician for a different medication.

Want more information?  www.cdc.gov/parasites/lice

 

Posted in General Medicine- Adults, infections, infections, Pediatrics, Uncategorized | Tagged , , , , , , , , , , | Comments Off on Head lice

Do your ears ring?

flickr.com/ photos/daeve/ 1620774512

flickr.com/
photos/daeve/
1620774512

You are not alone. Up to 18% of people are affected by tinnitus (the fancy word for ringing in the ears).  Thankfully, only 0.5% report that this has a severe effect on their daily life.

Tinnitus is the perception of sound in the ear that does not come from outside the body, from auditory hallucinations, or otherwise from within the body (like hearing a heartbeat in your ear).

This can occur all by itself, or it can occur with hearing loss.  Ringing in the ear can occur from an aspirin or quinine overdose.  Tinnitus can also be present even when hearing is normal.

Often tinnitus can have an insidious onset, meaning that it occurs so gradually that you are unaware that it is becoming louder.  It can last for years or decades.  Ringing can cause sleep disruption, an inability to concentrate, and depression.

There is NO clinically proven treatment for ringing of the ears.  The treatments with unknown effectiveness are as follows…

  • acupuncture,
  • antidepressants,
  • benzodiazepines,
  • electromagnetic stimulation,
  • ginkgo biloba,
  • hearing aids,
  • hypnosis,
  • psychotherapy,
  • tinnitus masking devices,
  • tinnitus retraining therapy.

Antidepressants may help with the associated depression if the ringing is disruptive to your life.

Hope this helps.

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